Hello! I am Sayan Patra.
I am a passionate science enthusiast with a Master’s degree in Biotechnology. I have a growing interest in Computational Biology, with a strong foundation in Bioinformatics, Systems Biology, and Omics data analysis. Currently, I am working to bridge the gap between biology and computer science by leveraging Artificial Intelligence and Machine Learning. In my leisure time, I enjoy listening to music, coding, and reading books.Created my own portfolio using HTML, CSS, and Javascript.
Downloaded a Breast Tumor dataset from Kaggle. Performed exploratory data analysis (EDA). Permormed Machine Learning to classify the diagnosis state of the tumor.
Downloaded RNA Seq data of Medulloblastoma (MB) from GEO database and performed DESeq2 analysis to find differentially express gene. Genes which were specific for subtypes were identified and logistic regression was performed for claasification of the sybtypes.
Created Deep Neural Network model of MLP and CNN to predict higher dimensional features of Molecular dynamic simulation from it's lower-dimensioanl features.
Treated Group-3 Medulloblastoma cells, HD-MB03 with NGI-1. Next, employed proteomics, metabolomics, lipidomics analysis using high throughput mass spectrometry. Performed primary and secondary data analysis. Visulize the data using R and python. Integrated each omics layer based on biological pathways.
Clonned Ftsz protein in E. coli vector for production of Ftsz protein. After that, employed protein purification techniques to isolate pure Ftsz protein. Next, bioinformatics and various spectrometry techniques like UV-Vis Spectrometry, Circular Dichorism, Spectroflurometry employed to decipher the structural and functional character of the protein.
Performed bioinformatics analysis like sequence alignment, and structural similarity analysis of primary, secondary, and tertiary structure of Botulinum Toxin B, Botulinum Toxin F, and Tetanus Toxin.
Isolated soil-bacteria from high pesticide content soil of Indian field using Cypermethrin containing media.Characterizes the bacteria based on biochmical test like gram staining, motility test, IMViC test, nitrate reduction, urease test, catalase test, TSI agar, Mc-Conky agar, EMB agar analysis. Isoalted plasmid from the bacteria using conventinal plasmid isolation.
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